Getting up and running with bioinformatics can be a heavy task, especially if the last time you used command-line commands was in the late 1980s/ early 1990s when we all thought any little tweak to the behemoth in the den was high level coding. All jokes aside, there are a lot of moving parts and I do find a little comfort in the simplicity that is bash. Over the next few weeks I’m going to spend a little time posting about the processes to get me going while I learn the workflow on my PC. First up - Mox (HYAK). This isn’t technically first, but it’s a great way to bring a few important steps together and we’ll backtrack as needed. Before we get started, check out this handy bash cheat sheet to help (re)familiarize you so you can tackle your behemoth. oldComp-image. Photo credit: awilkes8